Digital-native startups are ditching rigid databases for their agentic stacks

The data layer underneath an agentic system must handle variable schemas, vector embeddings, real-time retrieval, and ...
The Cipher Brief

After the Intelligence Cycle: A New Schema for AI-Native Intelligence Analysis

Recent discussion of artificial intelligence in intelligence analysis has consistently framed the technology as a means of accelerating an existing process. The intelligence cycle (collection, ...
InfoQ

Anthropic Reports Claude Now Handles 95% of Internal Analytics Queries

A monthly overview of things you need to know as an architect or aspiring architect. Unlock the full InfoQ experience by logging in! Stay updated with your favorite authors and topics, engage with ...
Nature

The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP

The acyl-coenzyme A-binding proteins (ACBPs) contain 26 highly conserved sequence positions. The majority of these have been mutated in the bovine protein, and their influence on the rate of two-state ...
PBS

Native Americans and Mount Rushmore

The creation of Mount Rushmore is a story of struggle — and to some, desecration. The Black Hills are sacred to the Lakota Sioux, the original occupants of the area when white settlers arrived. For ...
Complex

Balenciaga Becomes First Fashion House in Substack's Native Sponsorship Program

Balenciaga Leaves Twitter Following Elon Musk's Acquisition of Social Media Platform Fashion house Balenciaga has officially left Twitter following Elon Musk’s messy takeover of the social media ...